Most read this week
01Fatigue & Energy
9 min
02Supplements
7 min
03Thyroid Health
8 min
04Fatigue & Energy
8 min
05Sleep
7 min
06PCOS
9 min
07Mental Wellness
7 min
08Inflammation
8 min
Editor's Spotlight
Preventive Health
Achieving true wellness goes beyond just physical health. It encompasses a holistic approach, recognizing that different facets of our lives interconnect and influence our overall well-being. This guide explores the seven essential dimensions of wellness, offering insights and practical strategies for a more balanced and fulfilling life.
7 min read
Fatigue & Energy
Mitochondrial fatigue goes beyond simple tiredness, indicating issues with cellular energy production. Understanding its signs is crucial for addressing deeper metabolic imbalances and restoring vitality.
9 min read
Supplements
Delving into the science, this article compares berberine and metformin, two compounds often discussed for their roles in supporting metabolic health and blood sugar regulation. We examine the current research to provide a clear, evidence-based understanding of their mechanisms and applications.
7 min read
Most searched
Tap a symptom — we'll surface the root-cause stories, supplements, and clinician-reviewed guides our readers turn to most.
Editor's picks
Every story is hand-selected by our editors and reviewed by board-certified clinicians. We cite peer-reviewed research, disclose conflicts of interest, and update articles as the science evolves — no algorithms, no sponsored placements. How we curate medical content →
Editorial recommendations
Independently selected. We may earn a small commission — the recommendation is unaffected.
New & NotableStelo by Dexcom
OTC CGM that lets you see how food, sleep, and stress move your glucose.
Best OverallNordic Naturals
High-dose EPA/DHA in the form your body actually absorbs.
Editor's PickPure Encapsulations
Highly bioavailable magnesium for sleep, stress, and muscle recovery.
Deep dives
Investigations, narrative essays, and root-cause reporting on the science under modern wellness.
Browse the archive
The intricate communication network between your gut and brain, known as the gut-brain axis, is increasingly recognized for its pivotal role in mental health. This article explores how your gut microbiome influences mood, stress response, and overall cognitive function.
Understanding whether fasting insulin or HOMA-IR is the superior tool for detecting early insulin resistance is crucial for proactive metabolic health management. This article demystifies both tests, explaining their mechanisms and clinical relevance.
For many, the initial success of calorie restriction gives way to frustration as progress stalls. This article explores the physiological reasons why calorie restriction can backfire and offers sustainable strategies focusing on metabolic health.
Often overlooked, fiber is an essential macronutrient with profound impacts on metabolic health, digestion, and overall wellness. This article explores recommended daily intake and practical ways to incorporate more fiber into your diet.
Understanding your body's inflammation levels is a crucial step in proactive health management. This article demystifies inflammation markers, guiding you on which tests offer valuable insights for long-term well-being and which are less indicative for general screening.
The Metabolic Brief
Evidence-based metabolic health reporting in your inbox. Unsubscribe anytime.
The Metabolic Brief
Join 48,000+ readers getting the research, trends, and editor-vetted products that actually move the needle on metabolic health. Editor-reviewed. Zero fluff.
Latest
Sleep
Magnesium is a vital mineral, yet choosing the right form can be confusing. This article clarifies whether magnesium glycinate or citrate is best suited for your specific concerns, from sleep and anxiety to digestive support.
Fatigue & Energy
Ever feel profoundly tired, even after a full night's sleep? It might be more than just ordinary fatigue. Dive into the world of mitochondrial health and discover how your cells' energy powerhouses can impact your vitality.
Mental Wellness
The intricate communication network between your gut and your brain, known as the gut-brain axis, plays a profound role in shaping your mood and overall mental wellness. Understanding this connection is key to nurturing both physical and emotional health.
Wellness Trends
Cold plunges have surged in popularity, touted for everything from boosting metabolism to improving mood. But beyond the hype, who genuinely stands to benefit from a chilly dip, and who might be better off staying warm?
Nutrition
Fiber often takes a backseat to protein and fats, yet it's a critical component for maintaining a healthy metabolism, balanced hormones, and a happy gut. This article explores how much fiber you actually need and simple ways to incorporate more of this 'forgotten' macronutrient into your daily diet.
Preventive Health
Understanding your health goes beyond the surface. This article outlines 12 important lab tests that every woman should consider discussing with her doctor during her annual check-up to gain a more complete picture of her metabolic and overall health.
Thyroid Health
Many people are told their thyroid is "normal" based on TSH, but for some, symptoms persist. This article delves into the nuances of subclinical hypothyroidism, where TSH levels are within the reference range but not optimal, and how it can impact your well-being. Understanding this distinction is key to truly assessing your thyroid health.
Browse the archive
